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Encapsulation of ascorbic acid in ethyl cellulose nanoparticles was resulted in enhanced drug stability, increased anti-tyrosinase activity, and therefore improved skin whitening potential (Duarah et al., 2017b

In three-dimensional space, V730 is located near the coactivator binding site 84 and, along with M734 and I737 in the hydrophobic groove, allows the formation of a smoother and flatter surface that permits greater complementarity to FxxLF compared with the LxxLL motif (Figure 7C)

6,10,11 However, in severe poisoning, the selectivity for cardiac versus peripheral vascular effects can be profoundly decreased, making the cardiovascular effects less predictable